Cleanroom Equipment

Cleanroom equipment, also written clean room equipment, is the set of machines and enclosures that keep a controlled room clean while people and materials move through it and work inside it. Walls, HVAC and HEPA ceilings set the room's class; the equipment protects the most critical steps, controls how materials and people enter, and contains dust or organisms that the work releases.

Rooms are graded by how many particles they allow. ISO 14644-1 sets classes from ISO 1 to ISO 9: ISO 5 is the old Class 100, ISO 7 is Class 10,000 and ISO 8 is Class 100,000. In pharmaceutical manufacturing, EU GMP Annex 1 uses Grades A to D, where Grade A matches ISO 5 and Grade D matches ISO 8. Most of our equipment creates or protects an ISO 5 (Class 100) zone inside a room of a lower class.

If you are upgrading for revised Schedule M, our equipment checklist maps each requirement to the equipment that serves it.

At the entry points, air showers and garment cubicles prepare people, while pass boxes handle materials: static pass boxes between rooms of the same class, dynamic pass boxes where the classes differ.

Inside the room, critical open work happens under an ISO 5 zone: laminar air flow units when only the product needs protecting, bio safety cabinets when the operator must also be protected from biological material, and dispensing booths when powders are weighed or sampled and the dust must be kept away from the operator.

Planning the equipment together with the room layout avoids common problems: pass boxes that do not fit the wall thickness, booths too tall for the ceiling, or units placed where the room's own airflow disturbs them.